CAMBRIDGE, Mass., Sept. 14, 2021 – Pyxis Oncology (“Pyxis” or the “Company”) today announced the appointment of Jay M. Feingold, M.D., Ph.D., as Chief Medical Officer.

“Jay’s track record of success taking oncology ADC programs from discovery to commercial launch coupled with his deep understanding of clinical development perfectly align with our mission to improve the lives of patients with difficult-to-treat cancer,” said Lara Sullivan, M.D., Chief Executive Officer of Pyxis. “We look forward to working closely with Jay to build and execute our development strategies to advance our portfolio of next generation ADC and immunotherapy programs to the clinic.”

Dr. Feingold added, “I am excited to lead the clinical development activities for Pyxis’ robust portfolio which presents a significant opportunity to meaningfully impact the lives of patients with cancer. I am eager to work alongside the team to build on the Company’s impressive preclinical data, further strengthen the clinical strategy and shepherd its candidates towards the next stage of development to significantly improve the treatment landscape for patients with cancer.”

Dr. Feingold holds 20 years of experience in clinical development and medical affairs with a history of successfully bringing new hematology and oncology drugs to market. Most recently, Dr. Feingold served as Chief Medical Officer and Senior Vice President of ADC Therapeutics, where he led the clinical development of six ADCs for hematologic malignancies and solid tumors. Previously, Dr. Feingold worked as Vice President of U.S. Medical Affairs and Chairman of the Global Medical Affairs Oversight Committee at Daiichi Sankyo. Earlier in his career, Dr. Feingold held various executive roles of increasing responsibility at Wyeth Pharmaceuticals and was a member of the Departments of Medicine and Pediatrics and an Associate Director of the Bone Marrow Transplant Program at the University of Connecticut. Dr. Feingold earned his M.D. and Ph.D. from the Albert Einstein College of Medicine and trained in Pediatrics and Pediatric Hematology and Oncology at the UCLA Center for the Health Sciences.  

About Pyxis Oncology
Pyxis Oncology is developing a diversified portfolio of next-generation antibody-drug conjugates (ADCs) and monoclonal antibody (mAb) immunotherapies to target difficult-to-treat cancers and improve quality of life for patients. By advancing ADC technology, immunotherapy biology and leveraging its own proprietary target catalog, the Company is building a superior portfolio of biological products that may be used alone or in combination with other therapies. To discover, develop and advance its differentiated cancer therapies and technologies, Pyxis Oncology is also forging creative business models and alliances while leveraging its deep scientific understanding of the biology of the tumor microenvironment. For additional information, visit pyxisoncology.com.

Investor Contact
Ashley Robinson
LifeSci Advisors, LLC
arr@lifesciadvisors.com

Media Contact
Jason Braco, Ph.D.
LifeSci Communications
jbraco@lifescicomms.com

CAMBRIDGE, Mass., Sept. 7, 2021 – Pyxis Oncology (“Pyxis” or the “Company”) today announced the appointments of Freda Lewis-Hall, M.D., Thomas Civik, Darren Cline, and Mark Chin to its Board of Directors. These strategic appointments strengthen the company’s operational, clinical, and commercial expertise across its robust portfolio of biological product candidates targeting difficult-to-treat cancers.

“We are pleased to welcome these highly successful and seasoned industry leaders to our Board of Directors as we continue to advance our antibody drug conjugates and monoclonal antibody immunotherapies,” said Lara Sullivan, M.D., Chief Executive Officer of Pyxis. “These additions demonstrate our commitment to building a highly talented team with deep knowledge and insight that is extremely relevant to our mission and vision. Their combined experience will be instrumental in providing strategic oversight to support and guide Pyxis as we continue to evolve and grow our operations.”

Dr. Lewis-Hall has been on the frontlines of healthcare as a clinician, educator, researcher and senior executive in the biopharmaceuticals and life sciences industries during her 40-year career. She previously served as Chief Medical Officer, and Executive Vice President at Pfizer, Inc., where she was responsible for the safe, effective and appropriate use of the company’s medicines and vaccines. She also served as the company’s Chief Patient Officer, emphasizing patient engagement and inclusion. Prior to this, Dr. Lewis-Hall held various senior leadership positions at Vertex Pharmaceuticals, Inc., Bristol-Myers Squibb Co., Pharmacia, and Eli Lilly and Company.

Mr. Civik is a successful operating executive with a consistent track record of driving growth in new and established businesses. Under Mr. Civik’s leadership as CEO of Five Prime Therapeutics, the company was sold to Amgen in April 2021. He has extensive expertise in the oncology space, having worked closely with R&D as a commercial leader to develop and optimize products with significant patient impact. Mr. Civik brings nearly 30 years of experience in the biopharma industry, across several commercial leadership roles, including Vice President and Franchise Head at Genentech and Chief Commercial Officer at Foundation Medicine.

Mr. Cline has more than 30 years of experience in the biopharma industry as an accomplished commercial executive. He has collaborated with R&D across in all stages of development across numerous therapeutic areas including oncology. Mr. Cline has held various leadership roles of increasing scale and complexity at industry-leading companies including Amgen, InterMune, Alexion, Seagen and most recently, GW Pharmaceuticals, where he served as Chief Commercial Officer. Mr. Cline served on the Board of Stemline Therapeutics prior to the acquisition by Menarini Group.

Mr. Chin is a seasoned venture capital investor with significant experience as a Board Director of private and public biotech companies. As Managing Director, he has led Arix Bioscience into key portfolio company investments, including VelosBio, Amplyx Pharmaceuticals, Aura Biosciences, Harpoon Therapeutics and Imara. Mr. Chin previously held various executive roles at Boston Consulting Group, Gilead Sciences, Genentech, and most recently, Longitude Capital, where he focused on corporate strategy and investments in biotech and medical technology companies.

About Pyxis Oncology

Pyxis Oncology is developing a diversified portfolio of next-generation antibody-drug conjugates (ADCs) and monoclonal antibody (mAb) immunotherapies to target difficult-to-treat cancers and improve quality of life for patients. By advancing ADC technology, immunotherapy biology and leveraging its own proprietary target catalog, the Company is building a superior portfolio of biological products that may be used alone or in combination with other therapies. To discover, develop and advance its differentiated cancer therapies and technologies, Pyxis Oncology is also forging creative business models and alliances while leveraging its deep scientific understanding of the biology of the tumor microenvironment. For additional information, visit pyxisoncology.com.

Investor Contact
Ashley Robinson
LifeSci Advisors, LLC

Media Contact
Jason Braco, Ph.D.
LifeSci Communications
jbraco@lifescicomms.com

CAMBRIDGE, Mass., August 31, 2021 – Pyxis Oncology (“Pyxis” or the “Company”) today announced the recent appointment of Pamela Yanchik Connealy, M.B.A., as its Chief Financial Officer.  Ms. Connealy will be leading the Finance, Investor Relations and Human Resources functions at Pyxis.

“Over her extensive career, Ms. Connealy has developed a comprehensive track record of scaling and managing a rapidly growing biotech company,” said Lara Sullivan, M.D., Chief Executive Officer of Pyxis. “Her expertise touches all aspects of our operations and will be integral to us as we continue to advance our portfolio to the next stages of development. We are pleased to welcome her to our team and look forward to leveraging her experience as we work to improve the lives of patients with difficult-to-treat cancers.”

Ms. Connealy added, “I am honored to join the deep and talented Pyxis team.  I look forward to building on the strong foundation already in place and aiding in the development of our pipeline of potentially life-changing biologics.”

Ms. Connealy brings over 25 years of experience in financial and business operations with a strong track record of establishing processes to manage drug pipelines for biotech companies. Most recently, Ms. Connealy served as Chief Financial Officer and Chief Human Resources Officer at Immunovant, with responsibilities for finance, legal, IT and facilities. Previously, Ms. Connealy worked as Chief Financial Officer and Chief Operating Officer of Kiva. Earlier in her career she held various executive roles of increasing responsibility at the Bill & Melinda Gates Foundation, Salesforce and Genentech. Ms. Connealy earned her B.S. in Chemistry from Gannon University and an M.B.A. in Finance from the University of St. Thomas.

About Pyxis Oncology

Pyxis Oncology is developing a diversified portfolio of next-generation antibody-drug conjugates (ADCs) and monoclonal antibody (mAb) immunotherapies to target difficult-to-treat cancers and improve quality of life for patients. By advancing ADC technology, immunotherapy biology and leveraging its own proprietary target catalog, the Company is building a superior portfolio of biological products that may be used alone or in combination with other therapies. To discover, develop and advance its differentiated cancer therapies and technologies, Pyxis Oncology is also forging creative business models and alliances while leveraging its deep scientific understanding of the biology of the tumor microenvironment. For additional information, visit pyxisoncology.com.

Investor Contact
Ashley Robinson
LifeSci Advisors, LLC
arr@lifesciadvisors.com

Media Contact
Jason Braco, Ph.D.
LifeSci Communications
jbraco@lifescicomms.com

CAMBRIDGE, Mass., June 8, 2021 – Pyxis Oncology (“Pyxis” or the “Company”) today announced the appointments of Steve Monks, Ph.D. as Chief Technical Officer and Ritu Shah, PMP, as Chief Operating Officer. Additionally, Christoph Rader, Ph.D. and Anthony W. Tolcher, M.D., have joined the Company’s Scientific Advisory Board.

“It is with great pleasure that we welcome Dr. Monks and Ms. Shah to our team,” said Lara Sullivan, M.D., Chief Executive Officer of Pyxis. “Dr. Monks brings a breadth of manufacturing and regulatory experience that will help rapidly advance our rich portfolio of candidates to the next stage of clinical development. Additionally, Ms. Shah’s unparalleled industry and execution expertise will be instrumental as we expand our operations and progress towards our mission of transforming the lives of patients with difficult-to-treat cancers.”

Ronald Herbst, Ph.D., Chief Scientific Officer of Pyxis, added, “At Pyxis, we are thrilled to have Drs. Rader and Tolcher, with their tremendous experience in the development of antibody therapeutics, including antibody-drug conjugates, join our Scientific Advisory Board. Their deep expertise in antibody technology, conjugation of different payloads, and clinical development of new biologics will further strengthen the science at Pyxis and help guide our therapeutic programs towards the clinic.”

Dr. Monks added, “I am honored to join the Pyxis team alongside industry veterans who are committed to improving the treatment landscape for patients with cancer. The Company has rapidly established a robust, diversified portfolio that holds significant clinical potential. I look forward to leveraging my past experience to assist the Company in advancing its innovative biologics to the next stage of development.”

Ms. Shah said, “I am eager to apply my vast expertise in portfolio management and execution excellence to help support the Company during this period of exponential growth.”

Before joining Pyxis, Dr. Monks served as Senior Vice President of Development at Aura Biosciences. Before joining Aura, he was a member of the executive leadership team at Agenus. Dr. Monks received his Ph.D. from The University of Melbourne and a B.Sc. with first class honors in Zoology from the University of Queensland.

Most recently, Ms. Shah served as Vice President of Business Operations and Program Management of Levo Therapeutics. Prior to this, Ms. Shah was the Chief of Staff to the Chief Executive Officer and Vice President of Program Management at AveXis. Ms. Shah previously held various executive roles at Baxter, Baxalta, and Shire after starting her career at Accenture. Ms. Shah earned her B.Sc. from the University of Notre Dame in the Department of Chemical Engineering.

Dr. Christoph Rader is a Professor in the Department of Immunology and Microbiology at Scripps Research. Prior to this appointment, he was a Senior Scientist at the National Cancer Institute (NCI), National Institutes of Health (NIH). After earning his Ph.D. from the University of Zurich, Dr. Rader completed his postdoctoral training in antibody technologies at Scripps Research. In his independent career, he has pursued both antibody target and drug discovery strategies toward more specific and more potent treatment options for cancer patients, including target discovery efforts aimed at identifying new cancer cell surface antigens and drug discovery efforts based on antibody display, antibody engineering, and antibody conjugation methods.

Dr. Anthony W. Tolcher is the Chief Executive Officer, Founder and Director of Clinical Research at NEXT Oncology. In 2007, Dr. Tolcher became co-founder of South Texas Accelerated Research Therapeutics (START), a global clinical trial organization enabling first-in-human clinical trials with innovative cancer drugs within a global network. He has been involved in the earliest clinical studies of 17 approved agents for the treatment of cancer and has extensive experience and is considered a thought leader in the field of antibody drug conjugates. Dr. Tolcher is a board-certified medical oncologist and studied internal medicine at the University of Toronto and received his medical oncology training at the BC Cancer Agency in Toronto. His postgraduate research training was performed at the National Cancer Institute, National Institutes of Health Bethesda, MD. Dr. Tolcher is a Fellow of the Royal College of Physicians Canada (FRCPC), Fellow of the American College of Physicians (FACP), and Fellow of the American Society of Clinical Oncology (FASCO).

About Pyxis Oncology
Founded by Longwood Fund, Pyxis Oncology is building a differentiated portfolio of biologics, including antibody-drug conjugates (ADCs) and immunotherapies, to improve the lives of patients with difficult-to-treat cancers. Pyxis is employing site-specific conjugation technology to develop highly stable ADCs with enhanced therapeutic indexes. Pyxis is also advancing a diverse portfolio of immunotherapies that target broad immune regulators as well as novel immune checkpoints identified through its immuno-oncology and cold tumor discovery efforts. For additional information, visit www.pyxisoncology.com.

Investor Contact
Ashley Robinson
LifeSci Advisors, LLC
arr@lifesciadvisors.com

Media Contact
Jason Braco, Ph.D.
LifeSci Communications
jbraco@lifescicomms.com